A team of scientists from the University of Belgrade’s Medical Faculty has discovered the link between genetic code and susceptibility to Covid-related infection, as well as the subsequent appearance of more severe forms of the disease, the Science Fund announced.
The team, lead by the university professor and a corresponding member of the Serbian Academy of Arts and Sciences (SANU), Tatjana Simic, has made the discovery under the auspices of the project called AntioxIndentification, a special research programme on Covid-19,
The team produced results that will enable a personalized approach to the treatment of patients in the future, the press release of the Science Fund says. The project is funded by the World Bank and the project’s budget is 169,330 euros.
“Our research has shown that patients infected with Covid-19 carry genotypes with a lower activity of antioxidant enzymes, which have a lower antioxidant capacity which are therefore susceptible to a higher exposure to Covid-19, as well as a higher level of indicators of inflammation and coagulation,” said Professor Simic, noting that some of their findings have been recognized by the World Health Organization (WHO).
The Science Fund pointed out that, with its own funds and equipment, the team has isolated DNA from the blood of more than 500 subjects and formed a DNA biobank, which served as material for genotyping patients and control groups, and that approximately 9,000 genetic analyses were performed during the research.
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